Primary Job Title MD Primary Organization Forkhead BioTherapeutics
Location Kassel, Hessen, Germany Regions European Union (EU), Europe, Middle East, and Africa (EMEA) Gender Male
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Accili serves as the Russell Berrie Foundation Professor of Diabetes, Chief of the Endocrinology Division, and Director of the Diabetes Research Center at Columbia University Vagelos College of Physicians and Surgeons in New York City, and as an attending physician at New York Presbyterian Hospital.
Accili’s research has delved into the integrated
physiology of insulin action, and mechanisms of pancreatic beta cell failure. His most important contributions have been in the area of beta cell biology, and specifically in the observation that enteroendocrine cells have the potential to give rise to functional insulin-producing cells in the gut–a property that is being investigated as a therapeutic opportunity for type 1 diabetes. Germane to this discovery is the demonstration that beta cell failure, long held to be a consequence of cell death, can result from a dedifferentiation process, whereby beta cells lose the ability to make insulin, revert to a progenitor stage, and convert to other hormone-producing cells.
Accili’s body of work reflects significant, paradigm-shifting discoveries that hold promise for translating to novel approaches for diabetes prevention and care. He has received numerous awards, including the Banting Medal and the Lilly Award from the American Diabetes Association, the Claude Bernard Medal of the European Association for the Study of Diabetes, the University of Chicago’s Steiner Award, and the Endocrine Society’s Astwood Award.
