persistent inflammatory processes are the basis of several chronic inflammatory and autoimmune diseases, such as: nlrc4 - mas, adult onset still's disease, chronic obstructive pulmonary disease and many others ab2 bio is developing drugs that will not only treat the symptoms but also target the underlying causes of inflammation-based diseases extensive phase i and ib clinical trials demonstrated a high tolerance and an excellent safety profile of their drug. They have advanced clinical programs in nlrc4 mas and in adult onset still’s disease.