diseases by rapidly decreasing arterial cholesterol content and inflammation. LipimetiX's technology is based upon a platform of chimeric peptide mimetics of apolipoprotein E, a critical protein that directs cholesterol and triglyceride rich lipoproteins to receptors on the liver. LipimetiX's base peptide, AEM-28, has demonstrated remarkable VLDL cholesterol and triglyceride reductions in Phase 1 and Phase 2 human clinical trials. More potent analogs of AEM-28 are currently being developed for acute pancreatitis, refractory hypertriglyceridemia and genetically induced refractory hypercholesterolemia, orphan indications that lead to early cardiovascular disease. AEM-28 has been granted orphan drug designation from the FDA.