back over twenty years. Following divestiture of the heart valve business in 1999, Tissuemed focused its considerable scientific expertise on the development of surgical sealants. Five years of research and development yielded the TissuePatch™ product family, which is now at the core of the company’s activities. These unique surgical films have been designed specifically to help surgeons to effectively seal tissues against leakage air, blood and other fluids, including Cerebrospinal Fluid (CSF).