Gender Male
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Brian L. Kotzin, M.D., joined Nektar Therapeutics in April 2017 as Head of Clinical Development for the company’s immunology program and was appointed Senior Vice President, Clinical Development, in April 2018. In this role, he serves as the Development Program Lead for the company’s auto-immune and immuno-oncology investigational compounds
NKTR-358, NKTR-262 and NKTR-255. Dr. Kotzin has more than 30 years of experience in the fields of inflammation and immunology in academia and industry, and expertise in various autoimmune and inflammatory diseases, including systemic lupus erythematosus, rheumatoid arthritis and psoriasis. Prior to joining Nektar, Dr. Kotzin served as Vice President of Global Clinical Development and Head of the Inflammation Therapeutic Area at Amgen. During his 11 years at Amgen, he also served as Vice President of Translational Sciences and Head of Medical Sciences/Early Development, where he was responsible for the planning and execution of early-phase clinical development in all therapeutic areas as well as the discovery and implementation of pharmacodynamic biomarkers in clinical studies and clinical immunology support for clinical studies. After leaving Amgen in 2015, he became a consultant to groups involved in developing new therapeutics for systemic lupus erythematosus and other immune-mediated diseases.
Earlier in his career, Dr. Kotzin served as Head of Clinical Immunology in the Department of Medicine and Director of the Autoimmunity Center of Excellence at the University of Colorado Health Sciences Center in Denver. During his time in Denver, he was a professor in the Departments of Medicine, Pediatrics and Immunology at the National Jewish Medical and Research Center. In addition to previous academic posts in rheumatology and microbiology/immunology, Dr. Kotzin served as Chief of the Rheumatology Section at the Veterans Administration Medical Center in Denver.
Dr. Kotzin has authored more than 200 publications in medical journals, books and book chapters. He also served on the editorial boards of Arthritis and Rheumatism, The Journal of Immunology and the Journal of Clinical Investigation.
Dr. Kotzin received a B.S. in mathematics from the University of Southern California and an M.D. from Stanford University School of Medicine. He completed a residency in internal medicine and a fellowship in rheumatology and medicine at Beth Israel Hospital in Boston. He was a postdoctoral fellow in the Division of Immunology and Rheumatology at Stanford University School of Medicine. He is board certified in rheumatology and internal medicine.
