Primary Job Title Founder Primary Organization 
Mirimus
Location Columbus, Georgia, United States Regions East Coast, Southern US Gender Male
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Stephen Elledge is the Gregor Mendel Professor of Genetics in the Department of Genetics at Harvard Medical School and in the Division of Genetics at Brigham Women’s Hospital and is an investigator with the Howard Hughes Medical Institute. He received his B.S. in chemistry from the University of Illinois in 1978 and his Ph.D. in biology from the
Massachusetts Institute of Technology in 1983. He performed post-doctoral studies in the Department of Biochemistry at Stanford University. He is a former Helen Hay Whitney Fellow, American Cancer Society Senior Fellow, and Pew Scholar. He is a Member of the National Academy of Science, the American Academy of Microbiology, the Institute of Medicine and the American Academy of Arts and Sciences. Dr. Elledge’s research centers on the study of proteins that regulate the cell division cycle and cancer. He has developed innovative technologies to facilitate the identification of novel genes involved in cell division. Additionally, he has identified several key components of the cell cycle’s regulatory machinery and has made significant contributions to elucidate the biochemical pathways that regulate this machinery through synthesis of small inhibitory proteins and phosphorylation. In addition, his research focuses on the proteins that safeguard the genome by monitoring the presence of DNA damage, thus ensuring the integrity of chromosomes before cell division. Furthermore, Dr. Elledge has made significant contributions to the understanding of regulated protein stability through discovery of the SCF pathway, which controls the ubiquitin-mediated proteolysis of phosphoproteins. The SCF pathway has manifest significance in biology.
